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Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99%

Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99%

Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99%
Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99% Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99%

Large Image :  Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99%

Product Details:
Place of Origin: China
Brand Name: LIHE
Certification: ISO,GMP
Model Number: CAS 169590-42-5
Payment & Shipping Terms:
Minimum Order Quantity: 1KG
Price: 50USD/Kg
Packaging Details: 50KG/Drum
Delivery Time: 3-5days
Payment Terms: MoneyGram, Western Union, T/T, L/C
Supply Ability: 1000MT/YEAR
Detailed Product Description
CAS: 169590-42-5 MF: C17H14F3N3O2S
MW: 381.37 EINECS: 685-962-5
Boiling Point: 529.0±60.0 °C(Predicted) Color: White To Off-white
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Pharmaceutical Celecoxib Powder 169590-42-5


99% Pharmaceutical Celecoxib Powder

Pharmaceutical Celecoxib Powder CAS 169590-42-5 for High Purity 99%


Celecoxib Basic information
Indications and Usage Application in Particular Diseases Mechanisms of Action Pharmacokinetics Clinical Research Side Effects Warnings and Precautions
Product Name: Celecoxib
Synonyms: 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide Celecoxib;CJ-016377;CP-598107;PF-00345549;PHA-00846533;Celecoxib Solution, 100ppm;Celecoxib (200 mg);Celocoxib, >=99%
CAS: 169590-42-5
MF: C17H14F3N3O2S
MW: 381.37
EINECS: 685-962-5
Mol File: 169590-42-5.mol
Celecoxib Structure
Celecoxib Chemical Properties
Melting point 157-159°C
Boiling point 529.0±60.0 °C(Predicted)
density 1.43±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
pka 9.68±0.10(Predicted)
form powder
color white to off-white
Water Solubility 7mg/L(25 ºC)
Merck 14,1956


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Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99% 1

Pharmaceutical Celecoxib Powder CAS 169590-42-5 For High Purity 99% 2




Celecoxib can be quickly absorbed after oral administration, with peak concentration at about 3h. The peak concentration of a single oral dose of 200 mg is 705 ng/ml. After absorption, up to 97% binds to plasma proteins; the drug is widely distributed, with apparent volume of distribution (455±166)L. Metabolized in vivo through P450(CYP)2C9 liver enzyme metabolism. Combined with carboxylic acid and glucuronide through biotransformation, about 2% of original amount excreted in urine and feces. Half-life about 1h.
Drug disposition and pharmacokinetics vary with race and age, amplifying total mild liver absorption damage (AUC.) When ingested with high fat peak plasma concentration effects are extended 1-2h, and AUC increases 10%-20%. When taken with aluminum and magnesium antacids peak concentration is reduced 37%, and AUC decreases 10%. No interaction with warfarin, ketoconazole, or methotrexate (MTX.) Clinically significant interactions with fluconazole and lithium, reducing Cmax 37% and AUC 10%.




Celecoxib is indicated for the treatment of osteoarthritis and rheumatoid arthritis. Its use is contraindicated in individuals with hypersensitivity to sulfonamides or other NSAIDs. It should be used with caution in persons with hepatic disease. Interactions occur with other drugs that induce CYP2C9 (e.g. rifampin rifampin) or compete for metabolism by this enzyme (e.g. fluconazole, leflunomide). The most common adverse reactions to celecoxib are mild to moderate GI effects such as dyspepsia, diarrhea, and abdominal pain. Serious GI and renal effects have occurred rarely.



A selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis

For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis




Company profile:

Lihe Pharm Technology (Wuhan) Co., Ltd. has a registered capital of 3 million yuan, and our products have a great price advantage in Europe and South America. We are an experienced manufacturer of various apis, pharmaceutical intermediates, organic and inorganic chemicals. We provide samples to test the quality as a trial order, because I have confidence in the quality of our products, many foreign customers, received our goods will be consistent praise.



1. Through safe and fast freight distribution to all parts of the world (sea, land, air) home delivery, delivery within 3-5 days, we promise 100% delivery, if the package is not delivered, 100% redelivery or refund!

2. We have a group of high-quality engineers and experts to provide guidance for reagents, when you meet problems in the process of mineral processing, we can provide technical guidance.

3. Payment method :WU, T/T, Moneygram, Bitcoin Alibaba Gold member with high credit guarantee.

4. We double clear package tax, accept sample orders, can also provide sample test welcome to consult, we will give you a super cheap price.






Q1. Can I have a sample order for your products?

A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable. We provide free samples, but the freight will be borne by you, and the cost will be returned to you or deducted from your order later.

Q2. What about the lead time?

A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than

Q3. Do you have any MOQ limit for order?

A: Low MOQ, 10-100g for sample checking is available

Q4. How do you ship the goods and how long does it take to arrive?

A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.

Q5. How about the packing?

A: Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.

Q6: how do you control quality?

A: We will make samples before mass production and start mass production after sample approval. 100% inspection during production and random inspection before packaging.

Q7: which payment method do you accept?

A: For small orders, you can pay by wire transfer, Western Union, Moneygram transfer, Bank Tansfer, Bitcoin or Alibaba.

Q8: can you give me a discount?

A: Of course, it depends on your quantity

Q9: how to confirm product quality before placing an order?

A: you can get free samples for some products. You only need to pay for transportation or arrange express delivery to take samples for us. You can send us your product specifications and requirements. We will make products according to your requirements.

Q10: how do you deal with quality complaints?

A: first of all, our quality control will reduce the quality problem to nearly zero. If the actual quality problem is caused by

us, we will send you free goods for replacement or refund.

Q11: Are you trading company or manufacturer?

A: We are chemical factory in China. So we can provide wholesale price.

Contact Details

Contact Person: Resse

Tel: +8618186115724

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