Product Details:
Payment & Shipping Terms:
|
Product Name:: | TAK-438 | CAS:: | 1260141-27-2 |
---|---|---|---|
MF:: | C21H20FN3O6S | MW:: | 461.4634032 |
EINECS:: | 250-635-4 | ||
High Light: | Vonoprazan CAS 1260141-27-2,TAK-438 1260141-27-2 |
Vonoprazan CAS 1260141-27-2 Free Shipping to Door High Purity
Product Name: | TAK-438 |
Synonyms: | Vonaprazan;5-(2-Fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-methanamine 2-butenedioate (Vonoprazan);1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine;AK-438;Vonaprazan(TAK-438);vonoprazan(tak-438);Vonoprazan fumarate(TAK-438);vonoprazan(tak-438)1260141-27-2 |
CAS: | 1260141-27-2 |
MF: | C21H20FN3O6S |
MW: | 461.4634032 |
EINECS: | 250-635-4 |
Description:Vonoprazan fumarate (Takecab®), discovered and developed by Takeda and Otsuka, was approved by the PMDA of Japan in December 2014, and is indicated for the treatment of gastric ulcer, duodenal ulcer and reflux esophagitis. Vonoprazan fumarate has a novel mechanism of action called potassium-competitive acid blockers, which competitively inhibit the binding of potassium ions to H+, K+-ATPase (also known as the proton pump) in the final step of gastric acid secretion in gastric parietal cells. Vonoprazan does not inhibit Na+, K+-ATPase activity even at concentrations 500 times higher than that of their IC50 values against gastric H+, K+-ATPase activity. Furthermore, the drug is unaffected by the gastric secretory state, unlike PPIs.
Packaging:
≤50kg, express delivery recommended, usually called as DDU service.
≤500kg, air shipping recommended, usually called as CIF service.
>500kg, sea shipping recommended, usually called as FOB, CFR or CIF service.
For high value products, please select air shipping and express delivery for safety.
Our Company:Lihe Pharmaceutical Technology (Wuhan) Co., Ltd. is a pharmaceutical company integrating product development, production and chemical intermediates, specializing in the research, development, production and export of organic intermediates, pharmaceutical intermediates, chemical solvents and pesticides.Loacted in Hubei Province, involving pesticide, medicine, chemical industry, coating, dye, reagent,polyester, petrochemical and other fields. AOP provide excellent Droducts and products for customers according to quality, quantity andtime Service, established a good brand reputation and business reputation in the industry, won the trust and support of many customersat home and abroad.since its establishment, the company has always adhered to the principle of people-oriented, technology for survival, quality for credit, service tenet, consistent quality and reputation guarantee, continuous pioneering spirit of business is the cornerstone of our development.
Contact Person: Wendy
Tel: +8618186051243