About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsPharma Raw Material

High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib

High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib

High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib
High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib

Large Image :  High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib

Product Details:
Place of Origin: China
Brand Name: LIHE
Certification: ISO,GMP
Model Number: CAS 169590-42-5
Payment & Shipping Terms:
Minimum Order Quantity: 1KG
Price: 50USD/Kg
Packaging Details: 15KG/Drum
Delivery Time: 3-5days
Payment Terms: MoneyGram, Western Union, T/T, L/C
Supply Ability: 1000MT/YEAR
Detailed Product Description
CAS: 169590-42-5 MF: C17H14F3N3O2S
MW: 381.37 EINECS: 685-962-5
Boiling Point: 529.0±60.0 °C(Predicted) Color: White To Off-white
High Light:

Celecoxib Powder 99%


Pharmaceutical Celecoxib CAS 169590-42-5

High Purity Celecoxib Powder 99% for Pharmaceutical CAS 169590-42-5 Celecoxib


Celecoxib Basic information
Indications and Usage Application in Particular Diseases Mechanisms of Action Pharmacokinetics Clinical Research Side Effects Warnings and Precautions
Product Name: Celecoxib
Synonyms: 4-[5-(4-Methylphenyl)-3-trifluoromethyl)-1H-pyrazol-yl]benzenesulfonamide Celecoxib;CJ-016377;CP-598107;PF-00345549;PHA-00846533;Celecoxib Solution, 100ppm;Celecoxib (200 mg);Celocoxib, >=99%
CAS: 169590-42-5
MF: C17H14F3N3O2S
MW: 381.37
EINECS: 685-962-5
Product Categories: MONASIRUP;Pfizer compounds;Active Pharmaceutical Ingredients;All Inhibitors;Sulfur & Selenium Compounds;Celecoxib;Osteoarthritis and Rheumatoid Arthritis;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Stable Isotopes;API
Mol File: 169590-42-5.mol
Celecoxib Structure
Celecoxib Chemical Properties
Melting point 157-159°C
Boiling point 529.0±60.0 °C(Predicted)
density 1.43±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >20mg/mL
pka 9.68±0.10(Predicted)
form powder
color white to off-white
Water Solubility 7mg/L(25 ºC)
Merck 14,1956


Celecoxib can be quickly absorbed after oral administration, with peak concentration at about 3h. The peak concentration of a single oral dose of 200 mg is 705 ng/ml. After absorption, up to 97% binds to plasma proteins; the drug is widely distributed, with apparent volume of distribution (455±166)L. Metabolized in vivo through P450(CYP)2C9 liver enzyme metabolism. Combined with carboxylic acid and glucuronide through biotransformation, about 2% of original amount excreted in urine and feces. Half-life about 1h.
Drug disposition and pharmacokinetics vary with race and age, amplifying total mild liver absorption damage (AUC.) When ingested with high fat peak plasma concentration effects are extended 1-2h, and AUC increases 10%-20%. When taken with aluminum and magnesium antacids peak concentration is reduced 37%, and AUC decreases 10%. No interaction with warfarin, ketoconazole, or methotrexate (MTX.) Clinically significant interactions with fluconazole and lithium, reducing Cmax 37% and AUC 10%.


Indications and Usage

Celecoxib and Rofecoxib are two currently used COX-2 inhibitors. Successfully developed by GD Searle & Pfizer Co. (U.S.,) released in 1999, trade name: Celebrex.
Celecoxib is a nonsteroidal, anti-inflammatory agent with significant analgesic and anti-inflammatory effects, causing the lowest incidence of upper gastrointestinal tract ulcers and other complications. Used clinically to treat acute and chronic osteoarthritis and rheumatoid arthritis, with an anti-inflammatory analgesic role, relieving the signs and symptoms of osteoarthritis and rheumatoid arthritis.




Celecoxib is indicated for the treatment of osteoarthritis and rheumatoid arthritis. Its use is contraindicated in individuals with hypersensitivity to sulfonamides or other NSAIDs. It should be used with caution in persons with hepatic disease. Interactions occur with other drugs that induce CYP2C9 (e.g. rifampin rifampin) or compete for metabolism by this enzyme (e.g. fluconazole, leflunomide). The most common adverse reactions to celecoxib are mild to moderate GI effects such as dyspepsia, diarrhea, and abdominal pain. Serious GI and renal effects have occurred rarely.



A selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis

For relief and management of osteoarthritis (OA), rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, acute pain, primary dysmenorrhea and oral adjunct to usual care for patients with familial adenomatous polyposis




Company profile:

Lihe Pharm Technology (Wuhan) Co., Ltd. has a registered capital of 3 million yuan, and our products have a great price advantage in Europe and South America. We are an experienced manufacturer of various apis, pharmaceutical intermediates, organic and inorganic chemicals. We provide samples to test the quality as a trial order, because I have confidence in the quality of our products, many foreign customers, received our goods will be consistent praise.



1. Through safe and fast freight distribution to all parts of the world (sea, land, air) home delivery, delivery within 3-5 days, we promise 100% delivery, if the package is not delivered, 100% redelivery or refund!

2. We have a group of high-quality engineers and experts to provide guidance for reagents, when you meet problems in the process of mineral processing, we can provide technical guidance.

3. Payment method :WU, T/T, Moneygram, Bitcoin Alibaba Gold member with high credit guarantee.

4. We double clear package tax, accept sample orders, can also provide sample test welcome to consult, we will give you a super cheap price.




1: How to start orders or make payments?

You can send your Purchase order, or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma

Invoice with our bank details for your confirmation, then you can make payment accordingly.

2: How to make the payment?

We can accept Bitcoin, Western Union, MoneyGram,PayPal, etc.

3: What's your MOQ?

For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts

from 100g and 1kg.

4: When will you deliver the goods?

If we have inventory, generally we can arrange shipment after receipt of payment 2 to 3 days. If not, it will be decided by the

time of the factory production.

Contact Details

Contact Person: Resse

Tel: +8618186115724

Send your inquiry directly to us (0 / 3000)