LIHE PHARM TECHNOLOGY (WUHAN) CO.,LTD
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| CAS: | 103-16-2 | Product Name: | Monobenzone |
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| Melting Po Int: | 119-120 °C (lit.) | Boiling Point: | 297.96°C (rough Estimate) |
| Density: | 1,26 G/cm3 | Package: | As Your Requirement |
| High Light: | 103-16-2 Monobenzone Powder,GMP 4-Benzyloxyphenol |
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Product Specification:
| Monobenzone Basic information |
| Product Name: | Monobenzone |
| Synonyms: | HYDROQUINONE MONOBENZYL ETHER;Benzyl hydroquinone;BENZYL P-HYDROXYPHENYL ETHER;MONOBENZONE;PBP;P-BENZYLOXYPHENOL;P-HYDROXYPHENYL BENZYL ETHER;4-BENZYLOXYPHENOL |
| CAS: | 103-16-2 |
| MF: | C13H12O2 |
| MW: | 200.23 |
| EINECS: | 203-083-3 |
| Product Categories: | B;Bioactive Small Molecules;Building Blocks;C9 to C20+;Cell Biology;Chemical Synthesis;API intermediates;whiten agent;cosmetics;Organic Building Blocks;Oxygen Compounds;Phenols;API;SANODIN;Bifunctional Compounds (Building Blocks for Liquid Crystals);Building Blocks for Liquid Crystals;Functional Materials;treat Vitiligo;103-16-2 |
| Mol File: | 103-16-2.mol |
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| Monobenzone Chemical Properties |
| Melting point | 119-120 °C (lit.) |
| Boiling point | 297.96°C (rough estimate) |
| density | 1,26 g/cm3 |
| refractive index | 1.5906 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 10.29±0.15(Predicted) |
| form | Powder, Crystals, and/or Chunks |
| color | Off-white to beige to brown |
| Water Solubility | slightly soluble |
| Merck | 14,6248 |
Preparation
4-Benzyloxyphenol Synthesis: Add 2.63g (0.028mol) of hydroquinone to a 100mL conical flask, weigh 1.12g (0.028mol) of sodium hydroxide, add 8mL of water, wait for the sodium hydroxide to dissolve and add dropwise to the conical flask with hydroquinone, shake well, then add 15mL of DMF and 2.52g (0.02mol) of benzyl chloride, under microwave radiation power of 320W The reaction was cooled to room temperature at the end of the reaction. The reaction was first adjusted to alkalinity with 10% sodium hydroxide, filtered, and the filtrate was washed with 10% sodium hydroxide until the filtrate was colorless (the filtrate was hydroquinone bis(benzyl ether), which could be recycled). The filtrate was acidified with hydrochloric acid to make Monobenzone completely precipitated, and then washed by filtration and ice water, recrystallized with alcohol and water, and decolorized by activated carbon to obtain 2.55g of white solid, the yield was 63.79%.
Indications
Monobenzone (Benoquin) potently inhibits melanin production and destroys melanocytes. Like hydroquinone, monobenzone was originally introduced for the topical treatment of disorders of excess melanin pigmentation, including melasma. It is now used only to permanently depigment the remaining normally pigmented skin in patients with extensive vitiligo. Irritant and allergic contact dermatitis are common side effects.
Company profile:
Lihe Pharm Technology (Wuhan) Co., Ltd. has a registered capital of 3 million yuan, and our products have a great price advantage in Europe and South America. We are an experienced manufacturer of various apis, pharmaceutical intermediates, organic and inorganic chemicals. We provide samples to test the quality as a trial order, because I have confidence in the quality of our products, many foreign customers, received our goods will be consistent praise.
Advantages:
1. Through safe and fast freight distribution to all parts of the world (sea, land, air) home delivery, delivery within 3-5 days, we promise 100% delivery, if the package is not delivered, 100% redelivery or refund!
2. We have a group of high-quality engineers and experts to provide guidance for reagents, when you meet problems in the process of mineral processing, we can provide technical guidance.
3. Payment method :WU, T/T, Moneygram, Bitcoin Alibaba Gold member with high credit guarantee.
4. We double clear package tax, accept sample orders, can also provide sample test welcome to consult, we will give you a super cheap price.
Deatailed Photoes:
FAQ
1: How to start orders or make payments?
You can send your Purchase order, or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma
Invoice with our bank details for your confirmation, then you can make payment accordingly.
2: How to make the payment?
We can accept Bitcoin, Western Union, MoneyGram,PayPal, etc.
3: What's your MOQ?
For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts
from 100g and 1kg.
4: When will you deliver the goods?
If we have inventory, generally we can arrange shipment after receipt of payment 2 to 3 days. If not, it will be decided by the
time of the factory production.
Contact Person: Resse
Tel: +8618186115724
