Pharmaceutical Grade Oral Aeds Gabapentin CAS 60142-96-3 Antiepileptic Raw Material

Description

γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter that functions by binding to the GABA receptors located in the spinal cord. Gabapentin is a γ-aminobutyric acid (GABA) analogue that acts as an anticonvulsant with proven analgesic effects in various neuropathic pain syndromes such as Complex Regional Pain Syndrome type one (CRPS 1). It is also prescribed to multiple sclerosis patients to control dysesthesias and may be useful in reducing neuropathic pain caused by cancer and HIV infection. It does not bind to GABA receptors, does not influence neural uptake of GABA, and does not inhibit the GABA-metabolizing enzyme, GABA transaminase. Unlike GABA, which does not pass through the blood-brain barrier, gabapentin penetrates into the central nervous system and binds to the α₂δ-type voltage-gated calcium channels. The mechanism for the analgesic and anticonvulsant effects of gabapentin are not known.

Psychiatric use

Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.

Indications

Gabapentin (Neurontin) significantly decreases pain scores and sleep interference associated with PHN. An initial dose of 300 mg/day is increased over 4 weeks (900, 1,800, 2,400, 3,600 mg/day divided t.i.d.) until efficacy is obtained or side effects become intolerable.

Pregnancy

• The dose of it should be monitored carefully during pregnancy and after birth, and adjustments made on a clinical basis.
• No definite conclusion can be made as to whether gabapentin is associated with an increased risk of congenital malformations when taken during pregnancy. Gabapentin should not be used during pregnancy unless the potential benefit to the mother clearly outweighs the potential risk to the foetus.
• Gabapentin is excreted in human milk. Because the effect on the breastfed infant is unknown, gabapentin should be used in breastfeeding mothers with caution and only if the benefits clearly outweigh the risks.

Company profile:

Lihe Pharm Technology (Wuhan) Co., Ltd. has a registered capital of 3 million yuan, and our products have a great price advantage in Europe and South America. We are an experienced manufacturer of various apis, pharmaceutical intermediates, organic and inorganic chemicals. We provide samples to test the quality as a trial order, because I have confidence in the quality of our products, many foreign customers, received our goods will be consistent praise.

Advantages:

1. Through safe and fast freight distribution to all parts of the world (sea, land, air) home delivery, delivery within 3-5 days, we promise 100% delivery, if the package is not delivered, 100% redelivery or refund!

2. We have a group of high-quality engineers and experts to provide guidance for reagents, when you meet problems in the process of mineral processing, we can provide technical guidance.

3. Payment method :WU, T/T, Moneygram, Bitcoin Alibaba Gold member with high credit guarantee.

4. We double clear package tax, accept sample orders, can also provide sample test welcome to consult, we will give you a super cheap price.

FAQ

FAQ

Q1. Can I have a sample order for your products?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable. We provide free samples, but the freight will be borne by you, and the cost will be returned to you or deducted from your order later.
Q2. What about the lead time?
A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than
Q3. Do you have any MOQ limit for order?
A: Low MOQ, 10-100g for sample checking is available
Q4. How do you ship the goods and how long does it take to arrive?
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5. How about the packing?
A: Usually we provide the packing as 25 kg / bag or carton. Of course, if you have special requirements on them, we will according to you.
Q6: how do you control quality?
A: We will make samples before mass production and start mass production after sample approval. 100% inspection during production and random inspection before packaging.

Q7: which payment method do you accept?
A: For small orders, you can pay by wire transfer, Western Union, Moneygram transfer, Bank Tansfer, Bitcoin or Alibaba.
Q8: can you give me a discount?
A: Of course, it depends on your quantity
Q9: how to confirm product quality before placing an order?
A: you can get free samples for some products. You only need to pay for transportation or arrange express delivery to take samples for us. You can send us your product specifications and requirements. We will make products according to your requirements.
Q10: how do you deal with quality complaints?
A: first of all, our quality control will reduce the quality problem to nearly zero. If the actual quality problem is caused by
us, we will send you free goods for replacement or refund.
Q11: Are you trading company or manufacturer?
A: We are chemical factory in China. So we can provide wholesale price.