LIHE PHARM TECHNOLOGY (WUHAN) CO.,LTD
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| Categories: | Bulk Drug Intermediates | Other Name: | Tianeptine |
|---|---|---|---|
| Molecular Weight: | 436.95 | MF: | C21H25ClN2O4S |
| Appearance: | White Powder | Density: | 1.38 G/cm3 |
| CAS: | 66981-73-5 | Melting Point: | 129-131°C |
| Boiling Point: | 609.2ºC At 760 MmHg | Refractive Index: | 1.639 |
| High Light: | Tianeptine CAS 66981-73-5,99% Tianeptine White Solid |
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Tianeptine CAS 66981-73-5 White Solid high quality 99% purity in stock
Product Description:
| CAS | 66981-73-5 |
| Molecular formula: | C21H25ClN2O4S |
| Appearance: | White powder |
| Purity: | 99.9% |
| Sample: | Available |
| Shelf life: | 2 years |
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Uses:
Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant.
Manufacturing Process:
A solution of 27.6 g (0.16 mol) of freshly distilled ethyl 7-aminoheptanoate in 40 ml of nitromethane was added all at once and with mechanical stirring to a suspension of 26.2 g (0.08 mol) of 5,8-dichloro-10-dioxo-11- methyldibenzo[c,f]thiazepine(1,2) in 120 ml of nitromethane. The whole was heated to 55°C for 30 minutes, the solvent was then evaporated in vacuo and the residue was taken up in water. The crude ester was extracted with ether. After evaporation of the ether 36 g of crude ester were obtained, and 30 g (0.065 mol) there of were treated under reflux with a solution of 2.8 g (0.07 mol) of sodium hydroxide in 35 ml of ethanol and 25 ml of water. After one hour's refluxing, the alcohol was evaporated in vacuo. The residue was taken up in 150 ml of water.
The mixture was twice extracted with 75 ml of chloroform and the aqueous phase was evaporated in vacuo. The sodium salt was then dissolved in 150 ml of chloroform, the solution was dried over sodium sulfate and the product precipitated with anhydrous ether.
The salt was filtered off, washed with ether and dried at 50°C. 13 g of sodium 7-[8-chloro-10-dioxo-11-methyldibenzo[c,f]thiazepin-(1,2)-aminoheptanoate,melting with decomposition at about 180°C, were obtained.
Our Company:
Lihe Pharmaceutical Technology (Wuhan) Co., Ltd. is a pharmaceutical company integrating product development, production and chemical intermediates, specializing in the research, development, production and export of organic intermediates, pharmaceutical intermediates, chemical solvents and pesticides.Loacted in Hubei Province, involving pesticide, medicine, chemical industry, coating, dye, reagent, polyester, petrochemical and other fields. AOP provide excellent products and products for customers according to quality, quantity and time Service, established a good brand reputation and business reputation in the industry, won the trust and support of many customers at home and abroad.since its establishment, the company has always adhered to the principle of people-oriented, technology for survival, quality for credit, service tenet, consistent quality and reputation guarantee, continuous pioneering spirit of business is the cornerstone of our development.
Packing and Delivery:
FAQ
Q: How to start orders or make payments?
A:You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly. for payment can also be by western union ,money gram ,bitcoin ,that is very easy
Q: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q: What's your MOQ?
A:For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount?
A: Yes, for larger quantity, we always support with better price.
Q:How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we
will send you free goods for replacement or refund your loss.
Q:How to contact us ?
You can choose your interested products and send inquiry to us.
You can dial our telephone directly, you will get our reply.
Send Email to us.
Q:what is the shipping way ?
A: for small order ,we ship by air express ,like Fedex, TNT,DHL,EMS ,
for large order ,we can send by air to the air port and send by sea to the sea port.
Contact Person: Nicole
Tel: +8618186124117
