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Product Name:: | Capecitabine | CAS:: | 154361-50-9 |
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MF:: | C15H22FN3O6 | MW:: | 359.35 |
EINECS:: | 604-948-1 | ||
High Light: | 154361-50-9 Pharmaceutical Chemicals,CAS 154361-50-9 Capecitabine |
CAS 154361-50-9 Capecitabine Free Custom Clear Pharmaceutical Chemicals
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Description:
Capecitabine is a new oral fluoropyrimidine carbamate for patients with advanced neoplastic disease, approved as Xeloda for the treatment of refractory metastatic breast cancer after failure on Paclitaxel and an anthracycline-based chemotherapy regimen ; it is a prodrug of doxifluridine (5-fluorouracil ; 5-FU) activated by a cascade of 3 enzymes concentrated in human liver and cancer tissue, resulting in the selective release of 5-FU at the tumor site and offering a prolonged tumour exposure to 5-FU. Oral Capecitabine passes intact through the intestinal mucosa, is converted first by carboxylesterase to 5'-deoxy-5- fluorocytidine in the liver, then by cytidine deaminase to 5'-deoxy-5-fluorouridine in the liver and tumour tissues and finally by thymidine phosphorylase to 5-FU in tumors. Therefore, Xeloda is much safer and more effective than 5-FU (for example, in the HCT116 human colon cancer and the MX-1 breast cancer xenograft .models). |
Packaging:
≤50kg, express delivery recommended, usually called as DDU service.
≤500kg, air shipping recommended, usually called as CIF service.
>500kg, sea shipping recommended, usually called as FOB, CFR or CIF service.
For high value products, please select air shipping and express delivery for safety.
Our Company:Lihe Pharmaceutical Technology (Wuhan) Co., Ltd. is a pharmaceutical company integrating product development, production and chemical intermediates, specializing in the research, development, production and export of organic intermediates, pharmaceutical intermediates, chemical solvents and pesticides.Loacted in Hubei Province, involving pesticide, medicine, chemical industry, coating, dye, reagent,polyester, petrochemical and other fields. AOP provide excellent Droducts and products for customers according to quality, quantity andtime Service, established a good brand reputation and business reputation in the industry, won the trust and support of many customersat home and abroad.since its establishment, the company has always adhered to the principle of people-oriented, technology for survival, quality for credit, service tenet, consistent quality and reputation guarantee, continuous pioneering spirit of business is the cornerstone of our development.
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