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Acetophenetidin Phenacetin Pharma Raw Powder,
Pharma Raw Powder CAS 62-44-2
|Phenacetin Chemical Properties|
|Melting point||133-136 °C (lit.)|
|Boiling point||132 °C / 4mmHg|
|density||1.1248 (rough estimate)|
|storage temp.||Sealed in dry,Room Temperature|
|pka||pKa 2.2(H2O) (Uncertain);3.5(aqueous acetone) (Uncertain)|
|Water Solubility||0.076 g/100 mL|
Usage:Phenacetin, a painkiller, was the world’s first synthetic pharmaceutical drug. It was one of the first painkillers that was not derived from opium while at the same time being absent of antiinflammatory qualities. Phenacetinwas developed in 1878 by an American chemist, Harmon Northrop Morse. It was introduced into the pharmaceutical market in 1887. However, it was withdrawn in 1983 in the United States due to unacceptable levels of interstitial nephritis in patients and potential risks of tumorigenicity. Like in the United States, most Western countries did not ban phenacetin from marketing until 1983. Phenacetin is a component of APC (aspirin-phenacetin-caffeine).
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