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Product Details:
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Product Name: | Benzocaine | CAS: | 94-09-7 |
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EINECS: | 202-303-5 | MF: | C9H11NO2 |
MW: | 165.19 | Mol File: | 94-09-7.mol |
High Light: | Benzocaine Local Anesthesia Drugs,94-09-7 Benzocaine |
94-09-7 Benzocaine Local Anesthesia Drugs
Benzocaine | |
CAS NO | 94-09-7 |
White powder | |
Purity | ≥99% |
Items of analysis | Specification |
Consistent with the standard chart | |
Reactive identification | Orange red |
Melting point | 88ºC-92ºC |
Less on drying | ≤0.5% |
Comply with USP standards | |
Residue on ignition | ≤0.1% |
≤10 ppm | |
≤1.0% | |
98-102% |
Description:Benzocaine (ethyl p-aminobenzoate) is used topically by itself or in combination with menthol or phenol in nonprescription dosage forms such as gels, creams, ointments, lotions, aerosols, and lozenges to relieve pain or irritation caused by such conditions as sunburn, insect bites, toothache, teething, cold sores or canker sores in or around the mouth, and fever blisters. Benzocaine is a lipophilic local anesthetic agent with a short duration of action.Like most amino ester-type local anesthetics, it is easily hydrolyzed by plasma cholinesterase. Because of its low pKa, however, it is un-ionized under most physiological conditions and, therefore, can only bind to the lipid side of the local anesthetic receptor. It also can easily cross membranes into systemic circulation to cause systemic toxicities. Furthermore, being a PABA derivative, it has similar allergenic properties to procaine and is contraindicated with sulfonamide antibacterial agents.
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