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White Pregabalin Pharma Raw Material,
CAS 148553-50-8 Pregabalin
|Boiling point:||274.0±23.0 °C(Predicted)|
|Place of Origin:||China|
Description:148553-50-8 , an analog of GABA that is related to , has been extensively studied in the treatment of GAD, fibromyalgia, neuropathic pain, and partial complex seizures.It appears to act even more selectively on the a2-δ subunit of calcium channels found in brain than does . 148553-50-8 received FDA approval in late 2004 for use in treating neuropathic pain and epilepsy. In 2008, it became the first drug approved for the treatment of fibromyalgia.Even though prcgabalin reccived approval for the treatment of GAD in the European Union in 2006, the FDA has not approved 148553-50-8 for GAD in the United States as of this writing.With the consistent efficacy in clinical trials and the known safety of it in clinical expericnce, it is not completely clear what has held up approval of prcgabalin for GAD.There was reported concern of the risk-benefit ratio for the drug,given the hepatotoxicity seen in micc, but this has not proven to be a problem postrelease in humans. it is categorized as an anticonvulsant and analgesic. The drug is under re-review currently by the FDA. it has a potential for abuse and misuse. it is regulated as a Schedule V compound in the United States.
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