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| Product Name:: | Phenacetin | CAS:: | 62-44-2 |
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| MF:: | C10H13NO2 | MW:: | 179.22 |
| EINECS:: | 200-533-0 | Mol File:: | 62-44-2.mol |
| Melting Point: | 133-136 °C (lit.) | Boiling Point: | 132 °C / 4mmHg |
| High Light: | Acetophenetidin Phenacetin Pharma Raw,Phenacetin Pharma Raw Powder,Acetophenetidin Pharma Raw |
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Phenacetin CAS 62-44-2 white fine powder 99.9% Pharmaceutical raw materials
Product Description
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Product Name: |
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Synonyms: |
ACETOPHENETIDIN;ACETOPHENETIDINE;ACET-P-PHENETIDINE;ACETYL-P-PHENETIDINE;1-ACETYL-P-PHENETIDIN;4-ACETOPHENETIDIDE;4-acetophenetidine;4'-ETHOXYACETANILIDE |
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CAS: |
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MF: |
C10H13NO2 |
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MW: |
179.22 |
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EINECS: |
200-533-0 |
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Product Categories: |
Others;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;organic interme;Organics;Other APIs;API;62-44-2 |
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Mol File: |
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Phenacetin Chemical Properties |
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Melting point |
133-136 °C (lit.) |
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Boiling point |
132 °C / 4mmHg |
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density |
1.1248 (rough estimate) |
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refractive index |
1.571 |
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Fp |
2℃ |
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storage temp. |
Sealed in dry,Room Temperature |
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pka |
pKa 2.2(H2O) (Uncertain);3.5(aqueous acetone) (Uncertain) |
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form |
powder |
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color |
White |
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Water Solubility |
0.076 g/100 mL |
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Sensitive |
Hygroscopic |
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Merck |
147,204 |
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BRN |
1869238 |
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Stability: |
Stable. Incompatible with strong oxidizing agents, strong acids. |
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InChIKey |
CPJSUEIXXCENMM-UHFFFAOYSA-N |
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CAS DataBase Reference |
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IARC |
1 (Vol. 24, Sup 7, 100A) 2012 |
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NIST Chemistry Reference |
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EPA Substance Registry System |
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Safety Information |
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Hazard Codes |
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Risk Statements |
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Safety Statements |
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RIDADR |
UN 3077 9 / PGIII |
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WGK Germany |
3 |
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RTECS |
AM4375000 |
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TSCA |
Yes |
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HS Code |
29251995 |
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Hazardous Substances Data |
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Toxicity |
LD50 orally in rats: 1.65 g/kg (Boyd) |
description
Phenacetin, a painkiller, was the world’s first synthetic pharmaceutical drug. It was one of the first painkillers that was not derived from opiu m while at the same time being absent of antiinflammatory qualities. Phenacetinwas developed in 1878 by an American chemist, Harmon Northrop Morse. It was introduced into the pharmaceutical market in 1887. However, it was withdrawn in 1983 in the United States due to unacceptable levels of interstitial nephritis in patients and potential risks of tumorigenicity. Like in the United States, most Western countries did not ban phenacetin from marketing until 1983. Phenacetin is a component of APC (aspirin-phenacetin-caf feine).
USES
Phenacetin was used as an analgesic and fever-reducing drug in both human and veterinary medicine for many years. It was introduced into therapy in 1887 and was extensively used in analgesic mixtures until it was implicated in kidney disease (nephropathy) due to abuse of analgesics (Flower et al. 1985) and was withdrawn from the U.S. market in 1983 (Ronco and Flahault 1994, FDA 1998, 1999). Phenacetin also was previously used as a stabilizer for hydrogen peroxide in hair-bleaching preparations (IARC 1980, HSDB 2009).
image description
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Q3.What's your delivery time?
A:Usually most of products in stock and can ship it out within 3-5 working days after getting the payment. if not in stock , we will arrange the shipment in 7-15 working days
Q4.What's your MOQ
A:It is based on the different product. Some are 1kg and some are 25kg . Plesae be free to consult our salesman.
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