Product Details:
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Product Name: | Procaine Hydrochloride | Color: | White |
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CAS No: | 51-05-8 | EC-No.: | 200-077-2 |
Purity: | 99% | Supply Ability: | 100tons |
High Light: | Crystalline Procaine Hcl Powder,Procaine Local Anesthesia Drugs,Procaine hydrochloride |
Procaine hydrochloride CAS 51-05-8 99% crystalline powder Local Anesthesia Drugs
Product Specification:
Product Name: | Procaine hydrochloride |
CAS No: | 51-05-8 |
Molecular Formular: | C13H21ClN2O2 |
Molecular Weight: | 272.77 |
EINECS No.: | 200-077-2 |
Melting point: | 155-156 °C(lit.) |
Boiling point: | 195-196°C 17mm |
Place of Origin: | China |
Type: | Pharmaceutical Intermediate |
Appearance: | Crystalline Powder |
Color | Colorless to white |
Purity: | 99.9% |
Packing: | 1kg,25kg or as per requirement |
Application: | Local anesthetic |
Storage: | 2-8°C |
Sample: | available |
Shelf life: | 2 years |
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Local anesthetic:
Procaine hydrochloride is a topical anesthetic, which can block the nerve fiber conduction temporarilyand has a narcotic effect,strong effect, low toxicity, and non-addictive, but on the skin, mucosal penetration is weak, unsuitable for surface anesthesia, patients are used for infiltration, conduction and spinal anesthesia.
The structure of procaine hydrochloride with aromatic primary amino, easy oxidation discoloration pH, temperature, UV, oxygen and metal ions can accelerate the oxidation discoloration. The aqueous solution was stable in pH3.0~5. So preparation of procaine hydrochloride injection, it generally takes add acid to regulate pH 3.3 to 5.5, and strictly control the sterilization temperature and time. to 100 ℃ steam sterilization 30min circulation is appropriate, and should pay attention to shading, sealed save.
Chemical Properties:
Small, colorless crystals or white, crystalline powder; odorless; stable in air. Soluble in water and in alcohol at 25C; slightly soluble in chloroform; almost insoluble in ether; solutions acid to litmus. Because the ester bond in the structure can be hydrolyzed to produce p-aminobenzoic acid and diethylaminoethanol, under certain conditions, p-aminobenzoic acid can be further decarboxylated to produce toxic aniline. Procaine hydrochloride has aromatic primary amino groups in its structure, which can be easily oxidized and discolored. pH, temperature, ultraviolet light, oxygen and metal ions can accelerate the oxidation and discoloration.
Uses:
Procaine is a local anesthetic of the amino ester group that is primarily used as a topical anesthetic. Procaine is also used to control the pain of intramuscular injection of penicillin as well as in dentistry.
Application:
Procaine hydrochloride has been used as a component of Krebs Henseleit buffer for incubating the left ventricular cardiac tissue in its resting length. It has also been used as an inducer in M9 media for induction assay. It is a sodium channel blocker and DNA methylation inhibitor.
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Enterprise Certification:
Lihe Pharmaceutical Technology (Wuhan) Co., Ltd. is a pharmaceutical company integrating product development, production and chemical intermediates, specializing in the research, development, production and export of organic intermediates, pharmaceutical intermediates, chemical solvents and pesticides.Loacted in Hubei Province, involving pesticide, medicine, chemical industry, coating, dye, reagent, polyester, petrochemical and other fields. AOP provide excellent products and products for customers according to quality, quantity and time Service, established a good brand reputation and business reputation in the industry, won the trust and support of many customers at home and abroad.since its establishment, the company has always adhered to the principle of people-oriented, technology for survival, quality for credit, service tenet, consistent quality and reputation guarantee, continuous pioneering spirit of business is the cornerstone of our development, and the support and praise of..
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